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OBJECTIVES
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NOTES |
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1. |
What molecules were believed present in the
atmosphere of early earth? Absent? 47
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2. |
Describe the Miller – Urey experiment. Label the
parts of the apparatus that mimic the ocean, the atmosphere, rain and
lightning. What did it prove? 47
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3. |
Diagram and label an amino acid. Include the
amino group, R group, central carbon, and carboxyl group. 51
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4. |
Develop an evolutionary sequence from inorganic
molecules through multicellularity.
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5. |
What are isomers? What form of optical isomers is
found in the amino acids in cells? 53
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6. |
Understand how amino acids (monomers) can be
made
into proteins (organic polymers) by
condensation
reactions. (dehydration synthesis reactions)
54
How did this happen in the prebiotic soup?
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7. |
Understand
how proteins (organic polymers) can be
broken down
into amino acids (organic monomers) by
hydrolysis
decomposition reactions. 53
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8. |
Could
polymerization occur in the energy rich
environment
of early earth? 54
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9. |
Diagram the
reaction between two amino
acids to
form a dipeptide. Indicate all
functional
groups, molecule names, location
of the
peptide bond. 54
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10. |
Describe each level of protein structure,
identify the bonds involved, and demonstrate its shape. Consider:
primary, secondary, tertiary, and quaternary. 57-61
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11. |
How are
proteins denatured? What are molecular
chaperones? Why is correct
folding important in
protein
function? What are prions? 60-61
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OBJECTIVES
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NOTES |
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12 |
Describe the 7 protein types and their functions
in the cell. 63
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13. |
Use a graph to show the changes in energy
that occur during a chemical reaction when an
enzyme is present. Label reactants, transition
state, activation energy, products. 63
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14. |
Describe the characteristics of enzymes and
how they work. 64
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15. |
In a given example of a metabolic pathway, identify
the substrates, intermediates, enzyme, cofactor, energy carrier, and
end products. 66
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16. |
Explain the induced-fit model of enzyme
behavior. What is meant by activation energy? 67
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17. |
Explain how enzymatic activity is affected by
such factors as the amount of enzyme and
substrate present, change in temperature, pH,
and the presence of inhibitors. 68
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Group discussion |
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18. |
Use a diagram to show ATP’s role as the main
energy carrier in metabolism. Show chemical reactions involving the
degradation of ATP and the synthesis of ATP. Note input and output of
energy as well as loss and gain of phosphate groups.
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19. |
Do an energy time graph (ET) for any given
chemical reaction. 69
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20. |
Show how exergonic and endergonic reactions are
coupled. 69
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21. |
What are
the two classes of nucleic acid and
what is
their importance in living organisms? 75
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OBJECTIVES |
NOTES |
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22. |
What are the three components of the
nucleotide? 75
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23. |
How do nucleotides polymerize? 76
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24. |
Explain complementary base pairing in
nucleic acids. 81
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25. |
With a diagram, demonstrate how DNA
replicates itself. 83
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26. |
How is RNA similar to DNA and different
from DNA? 84
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27. |
What was RNA’s role in the prebiotic soup?
85
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28. |
What is the evolutionary significance of the round
ribozyme? What mechanism was responsible for the round ribozyme?
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29. |
Define the term “carbohydrate.” 90
Provide specific examples of carbohydrate monomers
and polymers. What are they called?
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30. |
What can you do if you are lactose intolerant? 93
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31. |
Identify and describe storage polysaccharides in
plants and animals and structural polysaccharides in animals and
bacteria. 95-96
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32. |
What are glycoproteins and what is their function?
97
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33. |
How do carbohydrates store and provide energy in
cells? 98-99
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34. |
How are the structural polysaccharides different
from energy providing polysaccharides? What benefits result from this
difference? 100
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